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O sal possibilita reduzir em média, 30% das doses de levodopa, necessários para o controle da sintomatologia, assim sendo, colabora para que não apareça ("long-term levodopa syndrome"). Indicações do Niar Está indicado para o tratamento da doença de parkinson idoipática em combinação com l-dopa ou l-dopa e carbidopa. Contra Indicações Absolutas do Niar hipersensibilidade individual demonstrada ao produto.
 - 07/03/2007
1- Kearon C, Ginsberg JS, Kovacs MJ, et al. Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism. N Engl J Med;349:631-9, 2003. 2- Prins HM et al. long term treatment of venous thromboembolic disease.Thromb Haemost;82:892-898,1999. 3- J, Fuster V, Ansell J, et al.
 - 07/03/2007
A mesalazina constitui terapia de primeira linha eficaz e bem tolerada na doença intestinal aguda leve a moderada, bem como para o tratamento de manutenção em longo prazo em pacientes com colite ulcerativa. Referência: Schroeder, KW. Role of Mesalazine in Acute and Long-Term Treatment of Ulcerative Colitis and Its Complications. Scand J Gastroenterol Suppl. 2002;(236):42-7. 3.
 - 07/03/2007
Arzneimittelforschung 1986; 36(4): 729-35. 6. Setnikar I, Palumbo R, et al. Pharmacokinetics of glucosamine in man. Arzneim.-Forsch/Drug Res 1993; 43: 1109-1113. 7. Reginster JY, Deroisy R, et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. Lancet 2001; 357(9252): 251-6. Dizeres Legais de Glucoreumin Registro MS-1.0084.9945 Farm. Resp.: Helcio Garcia de Souza - CRF-SP 37.
 - 03/04/2009
Ciclesonide is effective in the treatment of asthma: a 12-week, placebocontrolled study, presented at te 4th Triennial World Asthma Meeting 2004, February 16-19,2004; Bangkok, Thailand. Chapman KR, Patel P, Boulet LP, et al. Efficacy and long-term safety of ciclesonide in asthmatic patients as demonstrated in a 52 week long study. Eur Respir J. 2002;20(S38): Abstract 2328. Postma DS, Sevette C, Martinat Y, Schl sser N, Aumann J, Kafé H.
 - 26/05/2008
Blood 104:3483-9, 2004 8. Bonadonna G, Bonfante V, Viviani S, Russo AD, Villani F, Valagussa P. ABVD Plus Subtotal Nodal Versus Involved-Field Radiotherapy in Early-Stage Hodgkin’s Disease: Long-Term Results. J Clin Oncol 22:2835-41, 2004 9. Engert A, Franklin J, Eich HT, Brillant C, Sehlen S, Cartoni C, Herrmann R, Pfreundschuh M, Sieber M, Tesch H, Franke A, Koch P, de Wit M, Paulus U, Hasenclever D, Loeffler M, Muller R-P, Muller-Hermelink HK, Duhmke E, Diehl V.
 - 07/03/2007
Study Report Protocol 107, Novartis Pharma AG, Basel, Switzerland; 06-Apr-01. [77] 17. A multinational, multicenter, double-blind, randomized, active controlled, parallel group study design comparing the efficacy and safety of long-term treatment with valsartan, captopril and their combination in high-risk patients after myocardial infarction. Study Report Protocol 108. Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA; 17-Oct-03. [84] 18.
 - 23/08/2013
Once-daily pantoprazole 40 mg and esomeprazole 40 mg have equivalent overall efficacy in relieving GERD-related symptoms. Aliment Pharmacol Ther 2003;18(6):587-94. 27. Scholten T, et al. On-demand therapy with pantoprazole 20 mg as effective long-term management of reflux disease in patients with mild GERD: the ORION trial. Digestion 2005:72(2-3):76-85. 28. van Rensburg CJ, et al. Improved duodenal ulcer healing with pantoprazole compared with ranitidine: a multicentre study.
 - 15/05/2014
2. Grant SM., Clissold SP. Itraconazole: A Review of its Pharmacodynamic and Pharmacokinetic Properties, and Therapeutic Use in Superficial and Systemic Mycoses. Drugs 3 , 1989, 310 - 344. 3. Kokturk A et al. Efficacy of Three Short-term Regimens of Itraconazole in the Treatment of Pityriasis Versicolor. Journal of Dermatological Treatment 2002, 13: 185 - 187. 4. Zaitz C., Sampaio S. Avaliação da Eficácia e Tolerabilidade do Itraconazol no Tratamento da Pitiríase Versicolor.
 - 07/03/2007
4 BIBLIOGRAFIA Moore N, van Ganse E, Le Pare JM. The PAIN study: paracetamol, aspirin and ibuprofen new tolerability study: a large-scale, randomized clinical trial comparing the tolerability of aspirin, ibuprofen and paracetamol for short-term analgesia. Clin Drug lnvest. 1999; 18:89-98. Lesko SM, Mitchell AA. An assessment of the safety of pediatric ibuprofen: a practitioner-based randomized clinical trial. JAMA. 1995;273(12):929-33. Magni AM, Rosário N, Murahovschi J, et al.
 - 07/01/2019
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